Sunday, April 15, 2018

Dementia and Alzheimer's

A few days ago I received a request from a friend to share what I know about these diseases.  I have been researching them for years.  By publishing my thoughts here my friend can refer to them easily AND it may help others in the same position.  It also helps me consolidate what I know.

I have to emphasize that what is written here is purely MY OPINION and should not be used as an alternative to advice from a medical professional.  

This is what I am doing
 to mitigate the chance that I might get one of these diseases.  




According to this video on The Bredesen Protocol, there is now  SCIENCE supporting the nutritional and lifestyle advice that functional/restorative medicine doctors have been advocating FOR YEARS!   

If you aren't familiar with the terms, functional and restorative doctors don't treat symptoms, they look for the cause and work to eliminate it.  They make their money by curing you.  Here's a cartoon from one of my favorite restorative doctors, Dr. Peter D'Adamo:



I reviewed The Bredesen Protocol HERE.


Bredesen explains that the amyloid plaque characteristic of Alzheimer's is your body's way of protecting you from the three main causes of the disease. You can 'get' Alzheimer's from one or more of these conditions:
1. inflammation/glycotoxicity (glucose/insulin imbalance),
2. endocrine problems, and
3. toxins/infections.  

In order to design a treatment plan, multiple lab tests are done to determine your current levels of the markers for these conditions. 

Using the results of the tests, they design a program to first normalize and then OPTIMIZE your health.  .

If you read my review of The Bredesen Protocol you know that I think his program is incomplete.

I believe that heavy metal toxicity can contribute to both options (1) and (2) above, AND I believe that all of us have excess heavy metals because we cannot avoid them so *I* am going to address that part of the trifecta first. 

Here's what *I* plan to do:

I have a SWAMI, which is a personalized genotype diet plan that helps eliminate the food lectins that are problematic for my genotype.  (If you don't have one, you should! )

I had had all my amalgam tooth fillings removed years ago.  (If you still have even one have them removed by a mercury-safe dentist.  You are flooding your body with mercury every time you chew!)

FIRST, I'm having my genome decoded by Ancestry.com

SECOND, I will send the Ancestry.com results to Opus 23 (Opus 23 cannot use the results generated by 23AndMe)
If I have any MTHFR snps Opus23 will recommend ways to overcome them.  One of the things the MTHFR genes control are methylation pathways - the body's toxin removal processes - and these MUST be working properly before I start detoxing.
THIRD, once I know my methylation pathways are working, start detoxing using the products and protocols described in this Klinghardt video and this Klinghardt pdf.
I could order blood tests to determine which metals I need to detox; but, according to Dr. Klinghardt, we ALL have heavy metal toxicity because they are everywhere, and it's hard to test for them because your body sequesters them so they may not show up in blood, urine, or hair analyses.  I assume I have them and need to get rid of them.

Press HERE for part one - WHY I NEED TO DETOX

Press HERE for part two - HOW TO DETOX - the preliminary steps.

Press HERE for part three - HOW TO DETOX - mobilizing toxins.

Press HERE for part four - HOW TO DETOX - other considerations.


FOURTH:  Once I  have eliminated heavy metals and other toxins, like glyphosate, inflammation and endocrine problem should resolve themselves.  AT this point, I will order the lab tests recommended by Dr. Bredesen and will work to optimize the results.  I will need to find a functional/restorative doctor to help with this, preferably a Klinghardt practitioner.

(If you follow the Bredesen Protocol diet, make sure you also follow the lectin advice that both SWAMI and Opus23 provide.)




Dementia and Alzheimer's: The Bredesen Protocol

I have to emphasize that what is written here is purely MY OPINION and should not be used as an alternative to advice from a medical professional.  


A few days ago I received an email from a friend asking if I knew anything about Dr. Bredesen.  She had recently attended a presentation of The Broken Brain which recommended something called The Bredesen Protocol.  Pronounced Bread'-eh-sin, it's being hailed as both a preventative AND A CURE.   Really?  A cure?  I was skeptical.

I spent several days researching and I was pleased with what I found.  I was on the brink of signing myself up!  But when I tried to do that I found many reasons why I shouldn't go through with it, and I didn't.  I will describe in detail what I learned further down the page but here's my bottom line:

The Bredesen Protocol APPEARS to be both a preventative and a cure
that corroborates the conclusions I had reached on my own and 
presents a supposedly personalized plan for you to follow; 
BUT, his business model is horrendous!  
I refuse to support it:
It is EXTREMELY DIFFICULT to get information on the program and the practitioners
You have to PREPAY $900 just to be considered for the program
If you don't qualify, you do NOT get your $900 back.
Most of the program is NOT covered by insurance (of course) and it is VERY expensive.
They are training 'practitioners' at breakneck speed
The 'practitioners' appear to have wildly different qualifications
You cannot talk to the practitioners, to vet them, until after you PREPAY
The secrecy and insistence on prepayment make me suspicious and reluctant to trust them

If you're interested in how I came to this conclusion, keep reading.


Listening to this video, I was VERY IMPRESSED with Dr. Bredesen's knowledge.  Apparently, there is now  SCIENCE supporting the nutritional and lifestyle advice that functional/restorative medicine doctors have been advocating FOR YEARS!   

Based on the video mentioned above,  I wanted to know more.  It SOUNDED LIKE this man had connected all the dots I'd been reading about for the last 10 years.

There was no information online regarding where the doctor is located or how to make an appointment so I ordered his book.  While I was waiting for it to arrive I found this WONDERFUL website which summarized the book!

Based on this summary I believe the protocol has merit.

Bredesen explains that the amyloid plaque characteristic of Alzheimer's is your body's way of protecting you from the three main causes of the disease. You can 'get' Alzheimer's from one or more of these conditions:
1. inflammation/glycotoxicity (glucose/insulin imbalance),
2. endocrine problems, and
3. toxins/infections.  

In order to design a treatment plan, multiple lab tests are done to determine your current levels of the markers for these conditions.  They also test for leaky gut, leaky brain, and food sensitivities.  They claim that insurance will pay for these tests...

Using the results of the tests, they design a program to first normalize and then OPTIMIZE your health.  THAT IS REVOLUTIONARY, in my opinion.  Most doctors ignore everything in the 'normal' range and address only the abnormal readings.  

Even if I was not concerned about cognitive decline, I would do these tests!

Using the test results, the Bredesen Protocol claims to accomplish 4 things:
1. treat the underlying cause
2. change lifestyle factors to prevent it from reoccurring
3. restore all biomes
4. optimize hormones and other biomarkers.

While these goals are admirable, the changes you will need to make are not easy.

There is a gigantic list of the rules, foods, and supplements.  Most of the things on this list I have heard of (and approve of like getting enough sleep, avoiding EMFs, and reducing stress) but they appear to use the same protocol for everyone and I have a problem with that.

Now, remember, I am referencing a review of a book I haven't read yet, so I don't know whether the protocol devised by the clinic will differ for each person as they claim it will but if a personalized protocol is required then shouldn't the book specify that?

The recommended supplements can cost from $150-$450 per month and the supplement program is individualized based upon your synaptic needs as defined by the ReCODE report. 

Once you start the program, the labs and report are rerun periodically to monitor your progress. 


Here's what worries me about a one-size-fits all protocol:

The recommended diet is ketogenic - high in protein and fat, low in carbs, high in sulfur and goitrogens (cruciferous veggies), and lectins are not taken into account.  This will work for some people but could be disastrous for certain blood types.  He really needs to address blood type lectins.

Organic food is recommended by not required.  What is the point of detoxing if you're going to be introducing new toxins with every meal?

Regarding their toxin removal process the book lists some of the supplements they use but detoxing is not as easy as taking supplements.   They don't mention amalgam tooth fillings which are one of the MAIN sources of mercury toxicity.   If toxin removal isn't done correctly the toxins released from the places your body hides  them can be REABSORBED in places where they can do a LOT OF HARM!  Like your brain!  You MUST work with a qualified toxin removal specialist! 

Another thing they do not address (in the book) are genetic SNPs that impact all of the markers they test for.   For instance:

MTHFR genes control your methylation pathways - the routes your body uses to remove toxins.  If you have any MTHFR snps you may have trouble processing both B vitamins and sulfur.  A diet high in cruciferous veggies, like the one they recommend, will not be beneficial until you correct those snps.  In addition, IF you are toxic and you attempt to remove those toxins without FIRST correcting any MTHFR snps you will make yourself very sick. It would be like pouring sewage into a toilet that's plugged up downstream. It will overflow where you least want it to...


Personally, I would use parts of the book, not one of their practitioners.  Here's why: 

They are 'training' hundreds of practitioners at breakneck speed.  These practitioners do 3 things: order the lab tests, enter the lab results into the ReCODE program, and recommend supplements based on the resulting report.  How difficult can that be?  It must be EXTREMELY difficult based on what they charge....  Here are the hoops you have to jump through to get to talk to one of their practitioners:

When I contacted them and asked for a list of practitioners in this area I received a loooooong email recommending that I sign up for a Patient ReCode account using this 5 minute video as a guide.

Once you have created an account, you will be asked to submit the first of 12 MONTHLY $75 payments!   Eeep!  That's $900 just to check things out!   I'm curious, but not THAT curious. 

I (again) requested a list of practitioners in my area so I could inquire about their rates and received a list of about 20 within a 1000 mile radius (yes, they think 1000 miles is local).  But, *I* can't ask about their rates or philosophies, only the Bredesen office can do that.  And, if I find a practitioner whose rates are reasonable, I can't make an appointment until I pony up the $900 for the ReCODE account.

When I asked whether they could use the genetic data I had received from 23-and-me or Ancestry.com  they refused to answer.  When I asked whether they take any genes other than the APOE genes into account they refused to answer.  When I asked whether everyone follows the same diet with different supplements they refused to answer.   You're buying a pig in a poke.  They will not share one shred of information without that $900.  Why?  (I now think I know why!  Scroll to the bottom.)

When I asked who entered the data into their program the response was that only a trained practitioner could do it.  Once the report(s) is run, the practitioner then interprets the ReCODE report for you and monitors your progress while you follow the recommended program. 

If you prefer to work with your regular doctor - who can order all the labs if they're amenable to it - you'll have to arrange for them to teleconference with a Bredesen practitioner who will explain which labs are needed, and how to interpret the results.  You will, of course, pay for this service.


So...

Let's say there is a practitioner close by and their rates are manageable.  What do you get for your $900?  You would have access to the following:

UNLIMITED ReCODE reports (this is a good thing)
Complimentary Brain HQ Account (sounds like another good thing but what is it?)
Nutritional Guidelines for the protocol (crucial but isn't this in the book?)
Highest quality supplements delivered to you (might be useful)
Live Town Hall meeting with the doctor
Exclusive videos
Neural Agility Meditation
Patient Community Support Site
Exercise Tips
Sleep Hygiene
Several up to date health topics

ASSUMING you qualify for the program.  If you don't, you CANNOT GET A REFUND!  They will continue to charge $75/month for a full year. 

Honestly, this sounds like a shady racket to me.  If the protocol works as well as they claim it does,  why do they control access to the practitioners and require a non-refundable payment for reports they may never run?   Their business model makes me VERY SUSPICIOUS.


Here are some quotes from Bredesen's Facebook page:

The cost of participation is huge. $25,000 to $30,000. We went to a Dr in Tampa who was just trained in the protocol and the blood tests alone are $5,000.00. The Dr did not tell us anything about how the protocol works or even what's involved in it. We would gladly pay the money if it would help but I do not want to be taken advantage of when you will try anything to help or control the disease. But was advised by a number of people that it was not legitimate. My husband refused to go back to the Dr. If you can give me some insight that would be helpful.

Mary - for people with mild to moderate dementia, we definitely have success in halting and even improving the cognitive issues when we can uncover all of the factors that are contributing to the dementia and resolve these. It does require a lot of motivation from the patient and their family/caregiver to comply with the program. It requires changes in diet, daily exercise, daily brain training, daily meditation, and adequate sleep.

But the rewards can be huge! For the patients that I work with, I get a large majority of their laboratory testing done through their medical insurance. There are some specialty tests that may not be covered by insurance, but those might be on the order of $400-$500.

I hope you will find a practitioner to work with that you have confidence in. No one could promise that this program works for everyone, but we have definitely seen lots of success.

Wow, that's expensive. I looked at the training programs and even that is 1,550.00-1,800.00. I can't do that. My mom passed away from alzheimer's too.  

The book has been instrumental in being able to get potential patients to understand the multifactorial nature of cognitive decline. It provides a roadmap for them to follow and a tick box for me as a Bredesen trained practitioner. A great but no just for cognitive decline but healthy ageing. 

I am EXTREMELY disappointed in The Bredesen Protocol ReCODE program. We were extremely excited and hopeful to find a program that could help my dad with Alzheimer’s. However, to find a certified provider to get a consultation to learn more about the program and to see if my dad is even a good candidate, Dr. Bredesen’s ReCODE report makes you pay $75 just to get a name of a certified provider. But we did pay the $75 because want to learn anything that could possibly help my dad that is battling Alzheimer’s. We visited the certified provider. Unfortunately, we will not be able to participate in this program due to a number of reasons. And they will not give us a refund/cancellation of the ReCODE subscription which we will not be using at all, making us pay $75/month...total of $900 for nothing! When we aren’t able to use the site or Dr. Bredesen’s program. It is extremely disappointing to want to profit from families that are already suffering so much with a family member battling Alzheimer’s. Simply sad and heartless. I just feel it is really important for other people interested in the Bredesen Protocol program before signing up. 


BOTTOM LINE FOR ME:

I do believe Dr. Bredesen's protocol is worth trying but his business model SUCKS and I refuse to support it. 

The more I think about it, the more I'm convinced that the reason for this business model is to prevent the practitioners from 'stealing' their patients.  Using the book, which has been out since August 2017 and can't be recalled, it's possible for a practitioner to follow the protocol without using the proprietary software. In this light, the weird business model makes total sense.

Buy the book, have your doctor order the lab tests, and then use the book to interpret them and design a program for  yourself. Or, find a practitioner willing to work with you.


If you're toxic, make sure you work with a qualified practitioner to remove toxins safely!